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Bag Lifting Centrifuge for Antibiotic Intermediate Separation
SS316 basket type centrifuge
,Horizontal basket type centrifuge
,SS316 Screw basket centrifuge
Bag Lifting Centrifuge is a batch-type top discharge separation system designed for high-purity, heat-sensitive and contamination-sensitive materials.
It is widely used in antibiotic intermediate separation, where strict cleanliness, low residue, and crystal integrity are required.
The lifting bag discharge system allows gentle cake removal without mechanical scraping, reducing crystal damage and ensuring consistent product quality in pharmaceutical production.
This equipment is specially designed for pharmaceutical and fine chemical batch processes, including:
- Antibiotic intermediate crystal separation
- Pharmaceutical API wet crystal dewatering
- Fermentation broth solid-liquid separation
- High-purity fine chemical crystallization
- Sterile food additive purification
- Vitamin and bio-chemical intermediate processing
- Amino acid crystal recovery
- High-value small batch pharmaceutical production
- Cleanroom GMP production line separation
- Low-residue sensitive material handling
Antibiotic intermediates typically present the following challenges:
- Sensitive to contamination and metal ion residues
- Crystals easily damaged by high shear force
- Strict GMP cleaning requirements (CIP/SIP)
- High purity requirements after centrifugation
- Batch variability in crystal size distribution
- Need for complete mother liquor removal
Conventional discharge systems often cause:
- Crystal breakage
- Cross-contamination
- Incomplete discharge
- Cleaning difficulties
Our Bag Lifting Centrifuge provides a gentle and controlled batch separation solution:
1. Gentle Discharge System
The filter bag lifting design ensures no scraping damage, protecting fragile antibiotic crystals.
2. High Purity Separation
Optimized basket structure improves mother liquor removal efficiency, reducing residual moisture.
3. GMP-Compatible Design
- Clean weld structure
- No dead corners
- Optional CIP / SIP system
- Easy disassembly for validation
4. Stable Batch Operation
Each cycle is fully controllable:
- Feeding
- Filtration
- Washing
- Dewatering
- Bag lifting discharge
How the Bag Lifting Centrifuge Works in Antibiotic Intermediate Separation
Filter Cloth Installation → Slurry Feeding → Gentle Basket Filtration → Crystal Cake Formation → Optional Washing → Controlled Dewatering → Bag Lifting Discharge → Collection → Cleaning
During operation, antibiotic intermediate slurry is fed into the rotating basket under closed conditions.
Under centrifugal force, solvent passes through the filter medium while sensitive antibiotic crystals are retained and gently formed into cake, avoiding excessive shear or breakage.
After optional washing and final dewatering, the bag lifting system enables soft discharge, ensuring minimal crystal damage and maintaining high product purity suitable for pharmaceutical applications.
Technical Parameter
| Type | Diameter (mm) | Volume (L) | Capacity (kg) | Speed (rpm) | G-force | Power (kw) | Weight (kg) | Dimension(L*W*H)(mm) |
|---|---|---|---|---|---|---|---|---|
| PPBL-155 | 800 | 115 | 155 | 1500 | 1008 | 7.5 | 1800 | 1800*1050*1140 |
| PPBL-230 | 1000 | 170 | 230 | 1200 | 806 | 11 | 2800 | 2030*1300*1220 |
| PPBL-340 | 1200 | 250 | 340 | 800 | 431 | 11 | 3200 | 2300*1500*1350 |
| PPBL-400 | 1250 | 280 | 400 | 950 | 631 | 18.5 | 4200 | 2350*1550*1370 |
| PPBL-400-NA | 1250 | 400 | 540 | 950 | 631 | 22 | 5000 | 2350*1550*1520 |
| PPBL-650 | 1500 | 500 | 650 | 850 | 607 | 30 | 5200 | 2900*1900*1575 |
| PPBL-650-NA | 1500 | 600 | 800 | 850 | 607 | 37 | 5700 | 2900*1900*1800 |
| PPTD-300 | 1200 | 250 | 300 | 800 | 431 | 11 | 2500 | 2350×1650×1370 |
Gentle Crystal Protection
Bag lifting discharge avoids mechanical scraping, reducing crystal breakage and protecting sensitive antibiotic intermediates.
Pharmaceutical Hygienic Design
Food-grade stainless steel and polished contact surfaces ensure compliance with GMP and pharmaceutical production requirements.
High Purity Performance
Optional washing system helps remove residual mother liquor and improves final product purity.
Stable Batch Operation
Suitable for batch processes with consistent separation performance and repeatable product quality.
Easy Cleaning & Maintenance
Open-top structure allows convenient cleaning, inspection, and fast batch changeover.
Cost-Effective Solution
Compared with fully automatic systems, it provides lower investment cost while maintaining reliable pharmaceutical-grade separation performance.
Available Custom Options
| Item | Available Configuration |
|---|---|
| Contact Material | SS316L / SS304 food-grade stainless steel |
| Surface Finish | Pharmaceutical-grade polished (Ra ≤ 0.4 μm optional) |
| Basket Size | Customized according to batch capacity |
| Filter Cloth | Selected based on crystal size and filtration behavior |
| Washing System | Optional clean solvent / water cake washing system |
| Motor | Standard / explosion-proof motor (ATEX optional) |
| Sealing Design | Open-type / semi-sealed hygienic design |
| Control System | Standard control / PLC automation system |
| Cleaning Design | Easy-access CIP-friendly structure |
| Product Contact Parts | GMP-compliant pharmaceutical grade configuration |
| Downstream Connection | Dryer / vacuum dryer / collection bin / packaging line integration |
To recommend a suitable centrifuge solution, please provide:
- Material name
- Crystal particle size
- Production capacity (kg/batch or t/day)
- Solids content (%)
- Feed moisture (%)
- Target moisture (%)
- Slurry temperature
- Mother liquor composition
- Washing requirement (Yes/No)
- Contact material preference (e.g. 316L, Duplex, etc.)
- Downstream process (drying / packaging / storage)
1. Is this centrifuge suitable for antibiotic crystal protection?
Yes. The bag lifting discharge system minimizes mechanical force and prevents crystal breakage.
2. Can it meet GMP pharmaceutical standards?
Yes. The equipment supports GMP design, clean structure, and optional validation documentation.
3. What is the typical batch operation process?
Feeding → Filtration → Washing → Dewatering → Bag lifting discharge.
4. Can it handle solvent-based antibiotic intermediates?
Yes. 316L / 904L / Hastelloy materials are available for solvent resistance.
5. Do you support customized capacity?
Yes. We design according to batch volume, crystal properties, and production cycle.
We welcome distributor and agent cooperation in pharmaceutical intermediates, antibiotics, fine chemicals, and crystallization processes.
We support:
- Centrifuge selection and process guidance
- GMP hygienic design solutions
- Filter bag and system matching
- Spare parts and after-sales support
Please share your material details and process requirements. Our team will help recommend a suitable bag lifting centrifuge solution.
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